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The temporomandibular joints are complex structures containing muscles, tendons, and bones. Injury to or disorders of these structures can all result in pain in the jaw area. Additionally, other medical conditions not related to the TMJ may cause perceived pain in the jaw area. One of the most characteristic of these is the pain associated with coronary artery disease or heart attack, which typically occurs in the chest but can radiate (spread) to the jaw area.

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A seizure is the uncontrolled electrical activity in the brain, which may produce a physical convulsion, minor physical signs, thought disturbances, or a combination of symptoms.

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