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Other causes include conditions that affect the muscles and nerves of the eyelid as well as conditions that affect the skin and connective tissues of the eyelid. Rarely, tumors of the brain or eye area are the cause of drooping eyelids.

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For migraine prevention, beta-adrenergic receptor blockers (which inhibit part of the sympathetic nerve activity) such as metoprolol, atenolol, propranol, calcium channel blockers such as flunarizine, or antidepressive agents such as amitriptyline are often prescribed. Most medications for migraine prevention would produce a general relaxation effect.

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